Custom process

I want to ask something, can we make customize moving from imported drawing ? from Example i imported a machine, and i want making a move for the cyliner from the machine ?

Yes, it is possible to import custom 3D models and model them with your motions.
This requires access to the Modeling functionalities that are available in Visual Components Professional & Premium.
To get started, you can check the Academy course on component modeling: Basics of Component Modeling | Visual Components Academy

Can we making motion simulation for this cylinder ?

The cylinder should be simple to do. Simply extract it to a new node, and define a translational joint.
You can watch the beginning of the gripper modeling tutorial to see how this can be done.